Stress is defined in terms of its physical and psychological effects on a person, and can be a mental, physical and emotional strain. Workplace stress also known as occupational stress occurs when there is a discrepancy between the demands of the workplace and an individual’s ability to carry out and complete these demands. A number of factors contribute to workplace stress such as workload, isolation, isolation, toxic environment, lack of autonomy, relationship with co-workers, management bullying, harassment and lack of opportunities. Stress related disorders encompass a broader array of conditions, including psychological disorders, emotional strain, maladaptive behavior and cognitive impairment. In turn, these conditions may lead to poor work performance, higher absenteeism, lower productivity or even injury. Work stress is also associated with various biological reactions that may lead to compromised health such cardiovascular disease, development of musculoskeletal disorders or death in extreme cases. Kenexa Research Institute also found gender differences in the global survey of almost 30000 workers that female suffered more from workplace stress. Combination of organizational change and change and stress management techniques is often the most useful approach for the preventing work related stress and to enhance the performance of the employees.